Chinese Journal of Pharmacovigilance ›› 2016, Vol. 13 ›› Issue (1): 5-8.

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Effects of Xigui on Learning and Memory Function in Mice

DONG Shou-tang1, WANG Cheng-jun2, ZHANG Xu-qiang1, ZHU Gui-rong2, DU Yi-ming2   

  1. 1.Baoshan College of Traditional Chinese Medicine, Yunnan Baoshan 67800, China;
    2.Faculty of Pharmacy, Dali University, Yunnan Dali 671000, China
  • Received:2015-01-26 Revised:2016-02-25 Online:2016-01-08 Published:2016-02-25

Abstract: Objective To study the function of learning and memory of Xigui in mice. Methods The Methods of step-down test and step-through test were used to research the effects of Xigui on impairment of learning and memory in mice induced by scopomamine, sodium nitrite and ethanol. Results Compared with the model and solvent group, Xigui could significantly prolong the time of latency and decrease the number of errors on impairment of learning and memory in mice (P<0.05 orP<0.01). Conclusion Xigui could improve the learning and memory disorder of mice.

Key words: Xigui, mice, learning and memory

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