Immunotoxicity of traditional Chinese medicine containing Polygoni Multiflori Radix based on clinical signals

doi:10.19803/j.1672-8629.20220066

Abstract

Abstract: Clinically, most of the liver injuries caused by Polygonum multiflorum Thunb. and its preparations are immune specific liver injuries. The clinical risk signal mining of this type of liver injury focuses on specific constitution, basic diseases, gene markers, immune group libraries and serum metabolites. The onset of immune specific liver injuries is hidden and difficult to identify. This tentative exploration and mining of the immunotoxicity of Chinese herbal medicine containing Polygonum multiflorum Thunb. is expected to help clarify the priorities of subsequent clinical trials and provide reference for mining of clinical risk signals and the establishment of an early warning model of liver injury caused by Polygonum multiflorum Thunb.

Key words: Polygonum multiflorum Thunb., immune-specific, liver injury, clinical risk signals, immunotoxicity

CLC Number:

R961
R994

LEI Chao, WANG Zhifei, XIE Yanming. Immunotoxicity of traditional Chinese medicine containing Polygoni Multiflori Radix based on clinical signals[J]. Chinese Journal of Pharmacovigilance, 2022, 19(12): 1384-1387.

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