Chinese Journal of Pharmacovigilance ›› 2022, Vol. 19 ›› Issue (12): 1380-1383.
DOI: 10.19803/j.1672-8629.20210808

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Pharmaceutical care for a case of voriconazole combined with micafungin in the treatment of chronic obstructive pulmonary disease patients with pulmonary aspergillus infection

ZHANG Li1, CHEN Haitao1,△, CHEN Xueliang1, GAO Xiurong2,*   

  1. 1Chengdu Qingbaijiang District People’s Hospital, Chengdu Sichuan 610300, China;
    2Chengdu Medical College, Chengdu Sichuan 610500, China
  • Received:2021-08-26 Online:2022-12-15 Published:2022-12-21

Abstract: Objective To analyze the process of treatment and priorities of pharmaceutical care during the treatment of chronic obstructive pulmonary disease (COPD) complicated with invasive aspergillosis with voriconazole combined with micafungin. Methods Clinical pharmacists participated in the treatment and monitoring of a patient, selected drugs according to the metabolic kinetic characteristics of different drugs in the body, and provided pharmaceutical care during the treatment based on the condition of the patient. Results Upon participation in the treatment, the pharmacists recommended voriconazole combined with micafungin to alleviate the condition and prevent serious adverse drug reactions. Conclusion Selection of the right antibiotics is crucial to the efficacy of treatment of COPD with invasive aspergillosis. Clinical pharmacists should actively participate in pharmaceutical care of patients in critical condition.

Key words: voriconazole, micafungin, invasive pulmonary aspergillosis, chronic obstructive pulmonary disease, pharmaceutical care

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