Chinese Journal of Pharmacovigilance ›› 2020, Vol. 17 ›› Issue (8): 487-490.
DOI: 10.19803/j.1672-8629.2020.08.08

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Pharmaceutical Care for a Patient with Bradycardia Induced by Lenalidomide

TIAN Jixin, MIAO Wenjuan, LIAO Yingxi, ZHANG Ping, WANG Xiaodan, LI Shan, YAN Haihong*   

  1. Department of Pharmacy, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China
  • Received:2020-07-31 Revised:2020-07-31 Online:2020-08-15 Published:2020-07-31
  • Supported by:
    重大新药创制重大专项(2017ZX09304024)

Abstract: Objective To explore the pharmaceutical care for a patient with bradycardia induced by lenalidomide in order to promote the rational use of the drug. Methods A retrospective analysis was conducted of the pharmaceutical care involving clinical pharmacists for a patient with follicular lymphoma, who experienced secondary bradycardia after chemotherapy with lenalidomide. Clinical pharmacists assisted physicians in developing an individualized therapeutic regimen and practiced special pharmaceutical care in the drug therapy. Results Clinical pharmacists analyzed the causes of this case of bradycardia, and gave advice to physicians about how to select therapeutic regimens and adjust concomitant medications, which was taken and achieved very good curative effect. Conclusion There is a significant correlation between the occurrence of bradycardia and the time lenalidomide is administered. If symptoms of arrhythmia occur during the use of lenalidomide, clinical pharmacists and physicians should carefully analyze the medical and medication history to initiate early diagnosis and treatment so as to reduce the harm of adverse drug reactions and lead to a better prognosis.

Key words: lenalidomide, bradycardia, pharmaceutical care, follicular lymphoma

CLC Number: