Abstract: Objective To explore the role of a clinical pharmacist in the treatment of a patient with parenteral nutrition related hepatic damage so as to provide reference for rational use of nutritional drugs. Methods One clinical pharmacist participated in the treatment of a patient with hepatic insufficiency, who not only identified the cause of hepatic injury, but also suggested that the parenteral nutrition formula be adjusted to 500 mL of 50% glucose injection, 1 500 mL of 8.5% compound amino acid injection (18AA-V), and 250 mL of 20% medium / long chain fat emulsion injection. The rest of the recipes remained unchanged. The amount of PN was decreased gradually and replaced by enteral nutrition (EN). Results Physicians adopted the suggestions of clinical pharmacist so that such liver function indexes as alanine aminotransferase and alkaline phosphatase returned to normal. Conclusion The duration of PN use and the types of lipids in PN may further aggravate liver injury. The participation of a clinical pharmacist in pharmaceutical care for patients can assure effective and safe use of nutritional drugs, and minimize complications and adverse drug reactions.

Key words: insufficient parenteral nutrition, liver injury, clinical nutrition, pharmaceutical care, clinical pharmacist