Clinical application of ursodeoxycholic acid

doi:10.19803/j.1672-8629.20210604

Abstract

Abstract: Ursodeoxycholic acid is a natural hydrophilic bile acid derived from cholesterol, which can inhibit the reabsorption of cholesterol in the intestine and reduce the secretion of cholesterol into bile. Thereby reducing the saturation of cholesterol, it is mainly used clinically for the treatment of cholelithiasis, cholestatic liver disease, bile reflux gastritis, primary sclerosing cholangitis, etc. This article summarizes the clinical application of ursodeoxycholic acid and the recommendations of the guidelines, summarizes its application in diseases, adverse reactions and pharmaceutical monitoring, etc., and provides a reference for the reasonable clinical application of ursodeoxycholic acid.

Key words: ursodeoxycholic acid, clinical use, pharmaceutical care, drug therapy

CLC Number:

R975

SUN Xuelin, HU Xin, ZHANG Yatong. Clinical application of ursodeoxycholic acid[J]. Chinese Journal of Pharmacovigilance, 2022, 19(10): 1149-1153.

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