Research Progress on Pharmacology and Toxicology of the Volatile Oil Components from Evodia Fructus

Abstract

Abstract: Objective To summarize the current research status of pharmacology and toxicology of the volatile oil components from Evodia Fructus for further research on its relativity, and provide the literature accordance and research ideas. Methods References in the last decades at home and abroad about the volatile oil components from Evodia Fructus were collated, analyzed and summarized. Results The volatile oil is one of the main chemical composition of Evodia Fructus. Evodia Rutaecarpa olefin and Evodia lactone have been isolated from the volatile oil at present, which mainly has analgesic action, bacteriostasis and promoting sympathetic nerve-adrenal function, and so on. Modern toxicology studies showed that volatile oil can induce certain acute liver damage. Conclusion The volatile oil is efficacy material basis and toxicity material basis, but the research is isolated, lacks of relevance, so efficacy should be not only studied, but also toxicity is studied at the same time, to provide the experimental data and literature evidence for reasonable and safe development of the volatile oil from Evodia Fructus.

Key words: Evodia Fructus, volatile oil, components, pharmacology and toxicology

CLC Number:

R965
R285.5

YIN Li-shun， SUN Rong. Research Progress on Pharmacology and Toxicology of the Volatile Oil Components from Evodia Fructus[J]. Chinese Journal of Pharmacovigilance, 2016, 13(3): 162-164.

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