Abstract: Objective To investigate and analyze the medication rationality of injective proton pump inhibitors (PPIs) for inpatients in a third class general hospital,so as to promote rational application of injective PPIs. Methods A random 200 medical records of using injective PPIs in hospitalized patients in 2014 were statistical analyzed, including patients’gender, age, department, indication, drug variety, dosage, course of treatment, and commented irrational medication examples. Results Injective PPIs are widely used in clinic, there is a certain of unreasonable medication in parts of medical records, including drug unreasonable selection, no indication of drug use and longer courses, etc. Conclusion Injective PPIs medication standards should be formulated by hospital, and the use of injective PPIs should be strictly controlled in clinic, avoiding excessive and irrational use of PPIs, reducing the cost of drugs and adverse drug reactions.

Key words: injective proton pump inhibitor, irrational medication, case analysis