Chinese Journal of Pharmacovigilance ›› 2023, Vol. 20 ›› Issue (8): 935-938.
DOI: 10.19803/j.1672-8629.20230104

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One case of abnormal uterine bleeding caused by Baofukang suppository

CHANG Yongzhuo1, LI Ji2, ZHANG Xiaoyan2, ZHOU Chaofan3,*   

  1. 1Department of Pharmacy, Beijing Fengtai Hospital, Beijing 100070, China;
    2Department of Gynaecology, Beijing Fengtai Hospital, Beijing 100070, China;
    3Institute of Basic Theory of Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
  • Received:2023-02-27 Online:2023-08-15 Published:2023-08-07

Abstract: Objective To offer clinical pharmaceutical tips for the use of Baofukang suppository by retrospectively analyzing one case of abnormal uterine bleeding and reviewing literature. Methods The treatment process of one patient with chronic cervicitis was tracked, the causes of abnormal uterine bleeding after medication were analyzed, and related literature was retrieved. Results One patient with chronic cervicitis and vaginitis suddenly experienced abnormal uterine bleeding after using Baofukang suppository. After discontinuation of Baofukang suppository and medication with tranexamic acid tablets, vaginal bleeding stopped. When Baofukang suppository was used a second time, there was a large amount of vaginal bleeding accompanied by endometrial-like substances and abnormal menstrual cycle. After Baofukang suppository was discontinued, the patient experience no more abnormal uterine bleeding within six months. The menstrual cycle and volume returned to normal. Conclusion For patients without severe blood stasis but with spleen and stomach weakness or with qi and blood deficiency, Baofukang suppository should be used with caution to prevent breakouts and menstrual disorders. For patients with obvious qi stagnation and blood stasis but with full qi and healthy spleens and stomachs, Baofukang suppository can be used for a short period of time to avoid damaging the positive energy.

Key words: Baofukang suppository, zedoary turmeric oil, abnormal uterine bleeding, case analysis, adverse drug reactions

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