Chinese Journal of Pharmacovigilance ›› 2023, Vol. 20 ›› Issue (5): 579-582.
DOI: 10.19803/j.1672-8629.20220036

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Pharmaceutical care of a patient with Clostridium difficile infection and urinary tract infection during pregnancy

FAN Xiucong, DONG Xiaohui, CHEN Danxia, BAO Siwei, MA Yabin*   

  1. Department of Pharmacy, Tongji University Affiliated East Hospital, Shanghai 200123, China
  • Received:2022-02-17 Online:2023-05-15 Published:2023-05-16

Abstract: Objective To analyze one case of pregnancy with Clostridium difficile infection and urinary tract infection, explore the rationality of the anti-infection treatment and provide reference for clinical rational drug use. Methods A clinical pharmacist participated in the treatment of a pregnant patient with Clostridium difficile infection and urinary tract infection. By retrieving related literature, strictly following the evidence-based medical practice and taking the patient’s conditions into consideration, the clinical pharmacist assisted the doctor in formulating the anti-infection treatment plan. Oral metronidazole and venous piperacillin tazobactam were used to treat Clostridium difficile infection and urinary tract infection, respectively. Results The clinical pharmacist helped doctors cure the infections and ensured the safety of the mother and fetus. Conclusion Clinical pharmacists should follow evidence-based methods and formulate a plan in combination with individual conditions. For the medication of concurrent infections, they should weigh the advantages and disadvantages and cure infections as long as the safety of the mother and fetus can be ensured, which can manifest the value of clinical pharmacists in obstetrics and gynecology.

Key words: pregnant, Clostridium difficile infection, urinary tract infection, anti-infection treatment, rational drug use

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