Consideration of rational use of traditional Chinese medicine and pharmaceutical services for the elderly based on literature analysis

doi:10.19803/j.1672-8629.2022.06.03

Abstract

Abstract: Objective The factors of adverse drug reactions/events(ADR/ADE) caused by the use of proprietary Chinese medicines in the elderly and the rational drug use basis and pharmaceutical service suggestions. Methods Taking 268 varieties of Chinese patent medicines contained in the national catalogue of essential drugs (2018 Edition) as the search object, the case reports of ADR/ADE caused by Chinese patent medicines to the elderly published in Chinese journal databases such as CNKI, Wanfang Data and VIP database were systematically searched. The time is up to January 1, 2021. After judging the causal relationship, the neural network method was used to mine the influencing factors of ADR/ADE in the elderly. Excavate the relevant expressions about rational drug use of the elderly in traditional ancient books, and form the thinking of rational drug use and pharmaceutical services. Results A total of 373 cases of ADR/ADE using Chinese patent medicines in the elderly were collected, involving 88 kinds of Chinese patent medicines, involving systemic damage, skin and adnexal system damage. There was a strong correlation between the severity of ADR/ADE and the duration of medication, mode of administration, and combination medication. A total of 20 459 pieces of warning information about the elderly in ancient books were sorted out, involving drug contraindications, treatment principles, drug dosage, and drug administration methods. Conclusion Clinical attention should be paid to the elderly's self-medication, combined medication, overdose and ultra-course of treatment, etc., strengthen pharmaceutical services, and improve the level of rational drug use.

Key words: Chinese patent medicine, the elderly, adverse drug reactions, pharmacovigilance, pharmaceutical services, rational drug use

CLC Number:

MA Bingbing, ZHANG Xiaomeng, ZHANG Bing, LIN Zhijian, LYU Jintao. Consideration of rational use of traditional Chinese medicine and pharmaceutical services for the elderly based on literature analysis[J]. Chinese Journal of Pharmacovigilance, 2022, 19(6): 595-599.

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