Literature Analysis of Adverse Drug Reactions Induced by Articaine as Stomatological Medicine

doi:10.19803/j.1672-8629.2021.02.13

Abstract

Abstract: Objective To analyze the characteristics and regularity of adverse reactions induced by articaine as a stomatological medicine so as to provide reference for the prevention of adverse reactions and rational clinical use. Methods Using“articaine”“primacaine”“to”“allergy”and“adverse reactions”as the key words, the articles in the CNKI and Wanfang detabase published from January 2005 to December 2018 were searched for and retrieved. The literature was analyzed according to the inclusion and exclusion criteria. Results A total of 27 papers (29 cases) were included. Systems and organs involved in ADRs were mostly central and peripheral nervous systems, the cardiovascular system and respiratory system. ADRs occurred most frequently within 30 min of medication. Conclusion More attention should be paid to articaine-caused adverse reactions in stomatology. Precautions should be taken to prevent adverse reactions, especially common allergic reactions so as to reduce the damage of adverse reactions to patients.

Key words: articaine, department of stomatology, adverse drug reaction, literature review

CLC Number:

R988.2

XIA Lin, YANG Hongwen, WANG Fang. Literature Analysis of Adverse Drug Reactions Induced by Articaine as Stomatological Medicine[J]. Chinese Journal of Pharmacovigilance, 2021, 18(2): 160-163.

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