中国药物警戒 ›› 2022, Vol. 19 ›› Issue (10): 1154-1159.
DOI: 10.19803/j.1672-8629.20210301

• 综述 • 上一篇    下一篇

彝族药紫地榆的研究进展及其质量标志物预测分析

郗仲玟1, 田宇柔1,2,3, 冯玉1, 麻景梅1,2,3, 王鑫国1,2,3, 牛丽颖1,2,3,*   

  1. 1河北中医学院,河北 石家庄 050091;
    2河北省中药配方颗粒技术创新中心,河北 石家庄 050091;
    3河北省中药材品质评价与标准化工程研究中心,河北 石家庄 050091
  • 收稿日期:2021-03-31 出版日期:2022-10-15 发布日期:2022-10-17
  • 通讯作者: *牛丽颖,女,硕士,教授·博导,中药分析及药效物质基础研究。E-mail: niuliyingyy@163.com
  • 作者简介:郗仲玟,女,在读硕士,中药分析研究。
  • 基金资助:
    河北省自然科学基金资助项目(H2019423050); 河北省重点研发计划(20372502D); 中央引导地方科技发展资金项目(206Z2501G)

Research progress in Yi medicine Geranium strictipes Knuth and predictive analysis of quality markers

XI Zhongwen1, TIAN Yurou1,2,3, FENG Yu1, MA Jingmei1,2,3, WANG Xinguo1,2,3, NIU Liying1,2,3,*   

  1. 1Hebei University of Chinese Medicine, Shijiazhuang Hebei 050091, China;
    2Hebei TCM Formula Granule Innovation Center, Shijiazhuang Hebei 050091, China;
    3Hebei TCM Quality Evaluation & Standardization Engineering Research Center, Shijiazhuang Hebei 050091, China
  • Received:2021-03-31 Online:2022-10-15 Published:2022-10-17

摘要: 紫地榆(Geranium strictipes Knuth)为云南省特有的民族药,其药用历史悠久,常用于治疗便血、痔血、血痢、崩漏、水火烫伤、痈肿疮毒等,在彝族应用广泛。在对紫地榆化学成分、药理作用研究论述的基础上,从原植物亲缘学及化学成分特有性、传统功效及药性、新的药效用途、化学成分可测性等方面对紫地榆的质量标志物(Q-marker)进行预测分析,为明确紫地榆Q-marker和建立科学的质量控制方法提供依据。

关键词: 紫地榆, 鞣质, 酚酸, 抗氧化, 抗炎镇痛, 质量标志物

Abstract: As an ethnic medicine unique to Yunnan Province, Geranium strictipes Knuth has been long used in clinical medicine to treat blood in the stool, hemorrhoids, blood dysentery, uterine bleeding, water and fire burns, carbuncle and sore. It is widely used in people of the Yi nationality. Based on research on the chemical constituents and pharmacological effects of Geranium strictipes Knuth, predictive analysis is made of the Q-markers of this drug in terms of original plant phylogeny, specificity of chemical components, traditional efficacy and medicinal properties, new medicinal uses, and measurable chemical components in order to help clarify the quality markers of Geranium strictipes Knuth and establish workable quality control methods.

Key words: Geranium strictipes Knuth, tannins, phenolic acid, anti-oxidation, anti-inflammatory and analgesic, Q- marker

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