One case of serious liver injury induced by Xiaojin tablets

doi:10.19803/j.1672-8629.2022.02.22

Abstract

Abstract: Objective To explore the correlations between serious liver function injury and Xiaojin tablets. Methods The adverse reactions of one case of serious liver injury caused by Xiaojin tablets were analyzed to study the correlation with Xiaojin tablets. The mechanism by which the medicinal ingredients and preparations caused adverse reactions was investigated by searching literature. Results According to the RUCAM table specified in the Guidelines for Clinical Diagnosis and Treatment of Herb-induced Liver Injury, this patient was diagnosed with chronic drug-induced liver cell injury. The RUCAM score was 8 (most likely), and the severity level was 3. The side effects of Xiaojin tablets might have been related to the toxic components. Conclusion The serious liver injury caused by Xiaojin tablets is related to the patient's autoimmunity, drug composition and quality standard.

Key words: Xiaojin tablet, liver injury, Aconitum kusnezoffii Reichb, adverse drug reaction

CLC Number:

R969R994.11

YANG Xiaolu, CAO Shan, XIONG Bo, QIN Zhen, XIA Yun, QU Hong. One case of serious liver injury induced by Xiaojin tablets[J]. Chinese Journal of Pharmacovigilance, 2022, 19(2): 213-216.

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