Literature Review on 89 Cases of Adverse Reactions Induced by Niuhuangjiedu Tablets/Pills

Abstract

Abstract: Objective hrough investigating the characteristics and mechanism of adverse reactions induced by Niuhuangjiedu tablets/pills to find its risk factors and provide technical support for safe and rational use of drugs in clinic. Methods Using “Niuhuangjiedu pills”, “Niuhuangjiedu tablets”, “adverse reaction” and “to” as key words to search and retrieve articles in the CNKI database. Forty-four references which met the inclusion and exclusion criteria were extracted and analyzed. Results Systems-organs mainly involved in adverse reactions are skin and its appendages, systemic damage, gastrointestinal system damage, etc. Rash, fever, allergic reaction, and diarrhea are the most common reported adverse reactions. Anaphylactic shock which is life threatening is also reported in several cases. Conclusion It is important to pay attention to the adverse reactions caused by Niuhuangjiedu tablets/pills, strengthen clinical rational use of drugs, in order to prevent adverse drug reactions and ensure the safe drug use in clinic.

Key words: Niuhuangjiedu tablet, Niuhuangjiedu pill, adverse drug reaction, literature review

CLC Number:

R994.11

GU Bing. Literature Review on 89 Cases of Adverse Reactions Induced by Niuhuangjiedu Tablets/Pills[J]. Chinese Journal of Pharmacovigilance, 2016, 13(6): 359-363.

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