Chinese Journal of Pharmacovigilance ›› 2023, Vol. 20 ›› Issue (9): 1060-1063.
DOI: 10.19803/j.1672-8629.20220642

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Psoriasis aggravated by labetalol during pregnancy: a case report

ZHANG Qing1, ZHU Lei2, LIN Cunlian2, XIE Peitao1, YANG Junli1, SU Changhai1,*   

  1. 1Pharmacy Department of Ordos Central Hospital, Ordos Inner Mongolia 017000, China;
    2Obstetrics and Gynecology Department of Ordos Central Hospital, Ordos Inner Mongolia 017000, China
  • Received:2022-11-04 Online:2023-09-15 Published:2023-09-14

Abstract: Objective To study the applicability of labetalol hydrochloride tablets in the treatment of gestational hypertension with psoriasis so as to provide reference for safe clinical use of the drug. Methods One case of gestational hypertension with psoriasis aggravated by labetalol hydrochloride tablets in our hospital was analyzed. The mechanism of action and characteristics of skin rash caused by labetalol hydrochloride tablets were explored by referring to literature. Results Labetalol hydrochloride tablets aggravated psoriasis in this patient with hypertension during pregnancy. Conclusion Clinical pharmacists should be sensitive to the adverse drug reactions in the treatment of psoriasis in special populations. Beta-blockers should be used with caution in patients with hypertension complicated with psoriasis during pregnancy.

Key words: labetalol hydrochloride tablets, pregnancy, hypertension, psoriasis, adverse drug reaction

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