Abstract: Objective To retrospectively analyze the whole process of treating acute kidney injury after postoperative chemotherapy in a patient with rectal cancer so as to explore the role of clinical pharmacists. Methods Taking into consideration the adverse reactions of a rectal cancer patient after chemotherapy and his renal injury, the clinical pharmacist provided pharmaceutical care for the patient before chemotherapy, during treatment and after chemotherapy. Results Through individualized adjustment of the patient's chemotherapy regimen and symptomatic treatment of renal function injury, the clinical pharmacist was a great success in his effort to give clinical pharmaceutical care to the patient. Conclusion In the course of medication for a tumor patient, clinical pharmacists can use their knowledge and expertise to assist clinicians in providing technical support for individualized drug treatment, which can not only facilitate clinical practice, but also ensure rational medication.

Key words: rectal cancer, chemotherapy plan, renal injury, adverse drug reaction