Abstract: Objective To explore the causes of palpitation and muscle tremor induced by tranexamic acid sodium chloride injection and the treatment measures.Methods The diagnosis and treatment of a case of palpitation and muscle tremor induced by tranexamic acid sodium chloride were analyzed. Combined with literature search, the mechanism and countermeasures of panic and tremor induced by tranexamic acid sodium chloride were explored. Results Sudden palpitation and muscle tremor in patients with tranexamic acid sodium chloride may be related to excessive infusion rate, pay attention to the dose, speed, concentration can reduce the occurrence of adverse drug reactions, may also be a precursor to tranexamic acid-induced epilepsy, early EEG monitoring is helpful for diagnosis, some general anesthesia drugs and benzodiazepines may be used for treatment; or may be tranexamic acid-induced typeⅠdrug allergy reaction, and anti-allergic treatment should be given in time.Conclusion In the course of clinical use of tranexamic acid, it is necessary to strengthen observation. In case of adverse reactions, the drug should be stopped immediately, and corresponding emergency measures should be taken according to different situations.

Key words: tranexamic acid sodium chloride, adverse drug reaction, palpitation, muscle tremor, promethazine