Prevention of Adverse Reactions of Antibiotics in a Respiratory Department

doi:10.19803/j.1672-8629.2021.11.19

Abstract

Abstract: Objectiv eTo analyze the adverse drug reaction (ADR) that occur in a respiratory department and recommend precautions for the sake of rational use of antibiotics in clinic. Methods ADR reports of antibiotics in a hospital between January 31, 2016 and August 31, 2018 were retrospectively analyzed. The incidence of antibiotics-related ADR in different age groups, drug varieties, the time adverse reactions occurred, systems and organs involved and clinical manifestations were analyzed．A total of fifty-one ADR cases were included in this study. The characteristics of three cases of serious ADR were studied．ResultsElderly patients were more vulnerable to ADR in wards of a respiratory department. Levofloxacin, piperacillin-tazobactam and voriconazole were the top three drugs that were responsible for ADR. Most of the ADR were found within one day of treatment. Clinical pharmacists suggested precautions against ADR. Conclusion We should strengthen ADR monitoring of key drugs and elderly patients in order to ensure medication safety of patients by selecting the right drugs.

Key words: antibiotics, adverse drug reactions, rational administration, pharmaceutical care

CLC Number:

R969.3

WEI Yuanyuan, LI Fang, TAO Xiaomei, GU Hongyan. Prevention of Adverse Reactions of Antibiotics in a Respiratory Department[J]. Chinese Journal of Pharmacovigilance, 2021, 18(11): 1083-1086.

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