Abstract: Objective To explore the influence of Chinese Hospital Pharmacovigilance System(CHPS) on the quality of ADR reports. Methods The ADR reports submitted by two hospitals before the installation of CHPS and one year later were divided into the control group and study group. The indexes of the reports were scored in accordance with the "Guidelines for Quality Evaluation of ADR Reports (Tentative)". The difference in the number of ADR reports, quality of individual reports, overall quality of the reports and the total scores of the reports was compared between the two groups. Results The total number of ADR reports in the study group was 41.80% larger than that in the control group, and the number of serious ADR reports was 173.81% larger. The difference in the integrity and standardization of the reports between the two groups was statistically significant. The overall quality score and the total score of the reports in the study group were 34.28% and 21.41% higher than those in the control group, respectively. Conclusion CHPS is able to detect ADRs quickly, easily and accurately, which can significantly improve the quantity and quality of ADR reports in hospitals.

Key words: Chinese hospital pharmacovigilance system, adverse drug reaction, monicoring sentinel