中国药物警戒 ›› 2023, Vol. 20 ›› Issue (1): 101-105.
DOI: 10.19803/j.1672-8629.20220026

• 安全与合理用药 • 上一篇    下一篇

基于加权Topsis-秩和比法评价肿瘤科药品不良反应报告质量

吴娜1, 苏丹2,*, 王海坤1, 沈爱宗2   

  1. 1安徽医科大学附属亳州医院,安徽 亳州 236800;
    2中国科学技术大学附属第一医院,安徽省立医院,安徽 合肥 230001
  • 收稿日期:2022-02-15 发布日期:2023-01-19
  • 通讯作者: *苏丹,女,在读博士,主任药师,临床药学和循证医学。E-mail: dansu@ustc.edu.cn
  • 作者简介:吴娜,女,学士,主管药师,临床药学和循证医学。
  • 基金资助:
    国家科技重大专项重大新药创制（2020ZX09201004-007）

Quality evaluation of adverse drug reaction reports in oncology department based on weighted Topsis-rank-sum ratio method

WU Na1, SU Dan2,*, WANG Haikun1, SHEN Aizong2   

  1. 1Bozhou Hospital Affiliated to Anhui Medical University, Bozhou Anhui 236800, China;
    2The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei Anhui 230001, China
  • Received:2022-02-15 Published:2023-01-19

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摘要： 目的 建立药品不良反应（ADR）报告质量综合评价体系,为科学评价肿瘤科ADR报告质量提供参考。方法 参照相关评分标准及文件,制定ADR报告质量评价标准。使用加权逼近理想解排序（Topsis）与秩和比（RSR）相结合的方法,对2021年某院药学部收到的120例肿瘤科ADR原始报告质量进行评价并分档。结果 20例报告质量中等（Ci>0.570 0）;75例报告质量合格（0.360 0<Ci≤0.570 0）;25例报告质量不合格（Ci≤0.360 0）。报告主要存在问题包括ADR过程描述过于简短,药品信息错误、不全等。结论 基于加权Topsis-RSR法评价ADR报告质量,可避免单一方法的局限性,具有操作切实可行,结果具体科学的优点。评价结果表明某院肿瘤科ADR报告质量仍有待提升。

关键词: 药品不良反应, 报告质量, 加权Topsis法, 秩和比法, 肿瘤

Abstract: Objective To establish a comprehensive system for evaluating the quality of adverse drug reaction (ADR) reports and provide reference for objective evaluation of quality of ADR reports in an oncology department. Methods Quality evaluation standards for ADR reports were established according to the related scoring standards and documents. A combination of weighted Topsis and rank sum ratio (RSR) was used to evaluate and classify the quality of 120 original ADR reports submitted to the Department of Pharmacy by the Department of Oncology at Bozhou People’s Hospital in 2021. Results Twenty reports were of medium quality (Ci＞0.570 0), 75 reports were up to the standard (0.360 0＜Ci≤0.570 0) and 25 reports fell short of the standard (Ci≤0.360 0). The main problems included inadequate descriptions of processes of ADRs, incorrect or incomplete drug information. Conclusion Quality evaluation of ADR reports based on the weighted Topsis–RSR method can help avoid the limitations of a single approach. This method is feasible and effective. The results of evaluation suggest that the quality of ADR reports by the Department of Oncology at our hospital needs to be improved.

Key words: adverse drug reaction, report quality, weighted Topsis method, rank-sum ratio, oncology

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