人血白蛋白注射液的药品评价研究进展

doi:10.19803/j.1672-8629.2022.02.27

摘要/Abstract

摘要： 依据《中国药品综合评价指南参考大纲》对人血白蛋白（human serum albumin, HSA）注射液进行药品评价。查阅HSA注射液相关的诊疗指南、药典、药品说明书、文献及官方数据,对其安全性、有效性、顺应性、经济性等进行描述性分析。HSA注射液临床应用广泛且安全性好,但价格偏贵,医保仅限抢救、重症或因肝硬化、癌症引起胸腹水的患者（HSA低于30 g·L^-1）;HSA注射液已被多个国家的指南推荐用于肝硬化腹水、低血容量休克等疾病的治疗,但临床仍有不合理用药的情况发生。

关键词: 人血白蛋白注射液, 药品评价, 合理用药, 药品不良反应

Abstract: Human serum albumin (HSA) injections based on the “Guidelines for Comprehensive Evaluation of Chinese Drugs”were evaluated. The guidelines for diagnosis and treatment, pharmacopoeias, drug inserts, literature and official data related to HSA injections were consulted, while the safety, efficacy, compliance, cost, and clinical value of HSA were assessed. HSA injections are widely used in clinical practice and are quite safe, but they are too expensive and have not yet entered the national medical insurance catalogue. HSA injections have been recommended by guidelines in many countries for the treatment of such diseases as liver cirrhosis and hypovolemic shock, but there are still cases of inappropriate medication.

Key words: human serum albumin injection, drug evaluation, rational drug use, adverse drug reaction

中图分类号:

R994.11

鲁松, 杨萍, 杨黎, 董宪喆, 张兰. 人血白蛋白注射液的药品评价研究进展[J]. 中国药物警戒, 2022, 19(2): 228-232.

LU Song, YANG Ping, YANG Li, DONG Xianzhe, ZHANG Lan. Research progress in human serum albumin injections[J]. Chinese Journal of Pharmacovigilance, 2022, 19(2): 228-232.

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