阿托品联合盐酸戊乙奎醚致长时间视物模糊1例分析

doi:10.19803/j.1672-8629.2022.02.25

中国药物警戒 ›› 2022, Vol. 19 ›› Issue (2): 221-223.
DOI: 10.19803/j.1672-8629.2022.02.25

阿托品联合盐酸戊乙奎醚致长时间视物模糊1例分析

胡志红, 赵运华^*

承德市中心医院,河北承德 067000

收稿日期:2020-04-25 出版日期:2022-02-15 发布日期:2022-02-15
通讯作者: ^*赵运华,女,副主任医师,临床药学。E-mail：zhaoyhlt1984@sina.com
作者简介:胡志红,女,主任医师,临床药学。

One case of long-term blurred vision induced by atropine combined with penehyclidine hydrochloride injection

HU Zhihong, ZHAO Yunhua^*

Chengde Central Hospital, Chengde Hebei 067000, China

Received:2020-04-25 Online:2022-02-15 Published:2022-02-15

摘要/Abstract

摘要： 目的探讨阿托品联合盐酸戊乙奎醚致长时间视物模糊的发生机制。方法分析1例全麻术中联合应用阿托品及盐酸戊乙奎醚致长时间视物模糊患者的诊疗过程,结合文献,探讨阿托品联合盐酸戊乙奎醚引起长时间视物模糊的机制。结果患者全麻手术中联合应用阿托品及盐酸戊乙奎醚,术后发生视近物模糊,眼部检查后未见明显异常,未予特殊处理,于2周后自行恢复。结论阿托品联合盐酸戊乙奎醚致长时间视物模糊与两者均为抗胆碱药物有关,为防止发生不良反应,临床中尽量避免同类药物同时应用;确需同时应用时,为避免药物的协同作用,需酌情减量。

关键词: 阿托品, 盐酸戊乙奎醚, 视物模糊, 全身麻醉, 药品不良反应

Abstract: Objective To investigate the mechanism of blurred vision induced by atropine combined with penehyclidine hydrochloride. Methods The process of diagnosing and treating a patient with blurred vision caused by atropine and penehyclidine hydrochloride during general anesthesia was analyzed while the mechanism by which long-term blurred vision was caused by atropine combined with penehyclidine hydrochloride was investigated based on literature analysis. Results The patient had blurred vision postoperatively, but no obvious abnormality was found after eye examination, so no special treatment was given. The patient recovered spontaneously after 2 weeks. Conclusion The long-term blurred vision caused by atropine combined with penehyclidine hydrochloride is related to the fact that both of them are anticholine drugs. To prevent adverse reactions, drugs of the same type should not be used in combination. When the combination is absolutely necessary, it is critical to prevent the synergy of two drugs and reduce the dosage.

Key words: atropine, penehyclidine hydrochloride, blurred vision, general anesthesia, adverse drug reaction

中图分类号:

R969.3R994.11

胡志红, 赵运华. 阿托品联合盐酸戊乙奎醚致长时间视物模糊1例分析[J]. 中国药物警戒, 2022, 19(2): 221-223.

HU Zhihong, ZHAO Yunhua. One case of long-term blurred vision induced by atropine combined with penehyclidine hydrochloride injection[J]. Chinese Journal of Pharmacovigilance, 2022, 19(2): 221-223.

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阿托品联合盐酸戊乙奎醚致长时间视物模糊1例分析

One case of long-term blurred vision induced by atropine combined with penehyclidine hydrochloride injection

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