Chinese Journal of Pharmacovigilance ›› 2024, Vol. 21 ›› Issue (3): 349-351.
DOI: 10.19803/j.1672-8629.20230594

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One case of allergic shock caused by tocilizumab injection

CHEN Jie, ZHANG Bin, ZHAO Jun, ZHANG Chuanzhou*   

  1. Department of Pharmacy, the Affiliated Hospital of Qingdao University, Qingdao Shandong 266555, China
  • Received:2023-09-21 Online:2024-03-15 Published:2024-03-18

Abstract: Objective To analyze the characteristics of anaphylactic shock induced by tocilizumab injection in order to provide reference for clinical safe and rational drug use. Methods One case of anaphylactic shock caused by tocilizumab was analyzed. The related literature was reviewed while the causes, prevention and treatment of such adverse drug reactions were analyzed. Results According to the clinical manifestations of the patient and the correlation between the drug and the time of administration, this case of anaphylactic shock was considered to have been caused by tocilizumab. The symptoms of anaphylactic shock were relieved after effective anti-allergic treatment. Conclusion Clinicians should be wary of anaphylactic shock and other allergic conditions related to the use of tocilizumab, which should not be used in allergic patients.

Key words: tocilizumab, injection, allergic shock, adverse drug reaction, children

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