Abstract: Objective To provide references for municipal hospital to carry out the work of drug clinical trials. Methods The mode and experience of clinical trials in our hospital were introduced, and the main problems to carry out drug clinical trials in municipal hospital were analysed.Suggestions and thinkings were put forward to further enhance the level of drug clinical trials in municipal hospital. Results & Conclusion There were many proplems to carry out the work of drug clinical trials in municipal hospital such as incomplete organization configuration, insufficient experience of researchers, patients difficult acception of subjects. In order to promote the standardization of drug clinical trials, the municipal hospital should strictly abide by the requirements of national laws and regulations, perfect management organization, increase hardware and software investment, make full use of the advantages of professional and dominant resources, utilize external resources, fan out from a point to an area.

Key words: drug clinical trial, practice, thinking