Chinese Journal of Pharmacovigilance ›› 2016, Vol. 13 ›› Issue (9): 543-546.

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Research Progress on Pharmacological Effects and Clinical Applications of Xinkeshu Tablets

ZHANG Zhi-hui1, YANG Qian2, 3, 4, SUN Rong4, *   

  1. 1 Shandong Province Police General Hospital, Shandong Jinan 250002, China;
    2 Rizhao City Hospital of Traditional Chinese Medicine, Shandong Rizhao 276800, China;
    3 Shandong University of Traditional Chinese Medicine, Shandong Jinan 250355, China;
    4Shandong Academy of Chinese Medicine, Shandong Jinan 250014, China
  • Received:2016-10-31 Revised:2016-10-31 Online:2016-09-20 Published:2016-10-31

Abstract: Xinkeshu tablet is a traditional Chinese medicine composed of five kinds of medicinal plants, Salvia Miltiorrhiza, Pueraria Lobata, Panax Notoginseng, Crataegus Pinnatifida, Aucklandia Lappa. Pharmacology studies have shown that Xinkeshu tablet has many activities, such as improving blood rheology and blood flow dynamics, lowering blood cipids, improving the heart rate variability, protecting hearts from ischemia-reperfusion injury, improving endothelial function, against coxsackie virus in vitro, inhibiting liver enzyme activity, and inflammatory response. Xinkeshu tablet is usually used to treat hyperlipemia, coronary heart disease, arrhythmia, hypertension, cardiac neurosis, double heart disease, cerebrocardiac syndrome. This paper reviewed the main progress on studies of pharmacological effects and clinical applications of Xinkeshu in recent years, so as to provide a reference for the further research and development of this drug.

Key words: Xinkeshu tablet, pharmacological effect, clinical application

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