Research progress on pharmacological effect and structure-activity relationship of common cannabinoid compounds

doi:10.19803/j.1672-8629.20210549

Abstract

Abstract: Cannabis compounds have attracted extensive attention in recent years. Based on the current research globally, this review summarizes the pharmacological effects and the existing problems with several common cannabinoid compounds. Cannabinol, tetrahydrocannabinol and cannabinoid phenol have diverse pharmacological effects, such as anti-tumor, anti-inflammatory, antibacterial properties, immune regulation, mental regulation as well as neuroprotection. Cannabinoid compounds need to be monitored to prevent abuse. Therefore, the relationship between the chemical structure and the pharmacological activity should be clarified to reduce mental dependence and broaden clinical applications.

Key words: Cannabis sativa L., cannabidiol, tetrahidrocannabinol, canabigerol, mental effect, antibacterial, pharmacological effect, structure-activity relationship

CLC Number:

R994.11

WANG Chunqing, ZHANG Yuanyuan, LI Qian, DU Lina, JIN Yiguang. Research progress on pharmacological effect and structure-activity relationship of common cannabinoid compounds[J]. Chinese Journal of Pharmacovigilance, 2022, 19(12): 1388-1392.

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