Abstract: Objective To evaluate the status and issues of drugs related to hormone replacement therapy(HRT) in perimenopausal women in outpatient of our hospital. Methods The utilization of drugs related to HRT in perimenopausal women in outpatient of our hospital in the first quarter of 2013 was analyzed retrospectively in terms of varieties, consumption sum, DDDs, DDC, etc. Results The consumption sum of homone drugs in perimenopausal women, the total consumption sum and the ratio of the former to the latter in February 2013 were all lower. Duphaston, Climen, Progynova and Livial steadily dominated the first place on the consumption and constituent ratio lists in every month. The constituent ratio of Progynova showed an upward trend by month, while Livial was downward. Progynova, Climen, Duphaston and Ovestin were always on the top of the DDDs list in all months. In terms of DDC, Progesterone capsules and Duphaston ranked at the top 2 places in each month, followed by Livial. Conclusion Progynova, Climen, Duphaston and Ovestin were general drugs for HRT in perimenopausal women in our hospital. Progesterone capsules and Duphaston might be the heavy economic burden of patients.

Key words: perimenopause, hormone replacement therapy , analysis of drug utilization