Abstract: Objective To study the current state of construction of domestic hospital information system (HIS) and the national adverse drug reaction monitoring system (NADRMS), and to collect and confirm the demands of hospital for the connection of HIS and NADRMS. Methods The Methods of analyzing literature, consultation, questionnaire survey, interviewing and on-scene observation were used, 34 medical institutions from 6 provinces, namely Heilongjiang, Shanghai, Chongqing, Gansu, Yunnan, and Jiangxi were investigated by stratified sampling method according to geographical location. 362 medical workers were investigated, including heads of hospital information technology department and ADR monitoring personnel, and 362 questionnaires were received. Results 34 tertiary hospitals were all non-profit ones with more than 1 000 rated beds, the average number of in-service staff was 1 824, and average outpatient amount of the prior year was above 1.08 million person-time. 76.47% (26/34) of those hospitals mainly reported ADR reports manually, and didn’t build hospital ADR monitoring system. 85.29% of the hospital HIS were able to do secondary development. On the issue of the type of communicating HIS and NADRMS, 64.71% of the hospital selected the type of automatic exchange through the interchanger. The functional requirements of docking were mainly divided into four categories: the system maintenance, daily service, ADR enquiry and statistics, and clinical application and decision-making assistance, their rates of overall demand were 100%, 90.33%, 80.94% and 100% respectively. Conclusion This paper established functions of docking system that mainly include four types of demand function, namely the system maintenance, daily service, ADR enquiry and statistics, and clinical application and decision-making assistance.

Key words: hospital information system, national adverse drug reaction monitoring system, interconnection, demand