Abstract: ObjectiveTo determine the best formula of ointment of curcuma oil. MethodsThe best formula was determined by orthogonal design and high performance liquid chromatography methods, using appearance of the ointment and the contents of effective components as the test index. ResultsThe optimal formula was determined as followed: glyceryl monostearate 32 g, glycerin 70 mL, albolene 18 g, distilled water 500 mL. ConclusionThe ointment with high effective components obtained from this formula is stable.

Key words: orthogonal design, ointment of curcuma oil, base composition