围孕期妊娠用药暴露风险评价与药学实践进展

doi:10.19803/j.1672-8629.20220617

摘要/Abstract

摘要： 近年来,我国妊娠人群特点发生变化,孕期用药的比例相对较高,妊娠药物暴露风险也随之增加。围孕期药物暴露风险评价是保障孕期用药安全的重要内容。本文通过对围孕期药物暴露现状、药物与致畸风险及如何开展风险评价与药学服务等方面进行阐述,总结目前尚存的问题与挑战,为规范开展药学服务,完善我国风险评价体系提供参考。

关键词: 孕产妇, 围孕期, 用药安全, 药物暴露, 妊娠期, 风险评估, 药学服务

Abstract: With the changes in Chinese pregnant populations in recent years, the proportion of medication during pregnancy is relatively high, and the risk of exposure to drugs during pregnancy has also been increased. Therefore, risk assessment of drug exposure during pregnancy is critical to drug safety during pregnancy. This article reviews the current drug exposure during perinatal pregnancy, drugs and teratogenic risk, and ways to engage in risk assessment and pharmaceutical care before summarizing the problems and challenges so as to standardize the development of pharmaceutical care and provide reference for improving the risk assessment system in China.

Key words: pregnant and maternal women, perinatal, medication safety, drug exposure, pregnancy, risk assessment, pharmaceutical care

中图分类号:

R969.3

王然, 冯欣, 杜博冉. 围孕期妊娠用药暴露风险评价与药学实践进展[J]. 中国药物警戒, 2023, 20(7): 836-840.

WANG Ran, FENG Xin, DU Boran. Advances in risk assessment and pharmaceutical care of pregnancy medication exposure during perinatal period[J]. Chinese Journal of Pharmacovigilance, 2023, 20(7): 836-840.

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