药物警戒在妊娠期药物治疗中的应用现状及建议

doi:10.19803/j.1672-8629.2022.03.10

摘要/Abstract

摘要： 目的探索药物警戒在妊娠期药物治疗中的应用现状。方法概述不同国家和地区药物警戒的发展情况,分析妊娠人群一般用药特征,根据妊娠期用药安全特点讨论相应规则和实例,针对现状提出完善妊娠期药物警戒的建议。结果妊娠人群在孕期内使用药物较普遍,而其生理及心理状态会直接影响药物疗效和药品不良反应发生。结论建议通过建立妊娠期药物警戒系统、健全数据体系和加强全球范围内交流协作来探索妊娠期药物警戒的应用。

关键词: 药物警戒, 妊娠期, 药物治疗

Abstract: Objective To explore the current applications of pharmacovigilance in drug therapies during pregnancy. Methods The developments of pharmacovigilance in different countries and regions were summarized. The characteristics of common medications in pregnant populations were analyzed. According to the characteristics of safe medications during pregnancy, the related adverse reactions were investigated, the patterns of safe medications were explored, and the applications of pharmacovigilance during pregnancy were discussed. Finally, suggestions for improving pharmacovigilance during pregnancy were offered. Results In recent years, pharmacovigilance at home and abroad developed rapidly in order to better evaluate drug safety and guide clinical use. Different countries and regions established corresponding pharmacovigilance systems. The pregnant were a special medication group. Due to various needs, medications were common during pregnancy. Changes in the physiological and psychological status of pregnant women during could directly affect the efficacy of medications. The incidence of adverse drug reactions after medication during pregnancy was high. Conclusion Attention should be paid to the safety of medications during pregnancy and more effective pharmacovigilance systems during pregnancy should be established.

Key words: pharmacovigilance, pregnancy, drug therapy

中图分类号:

R969.3

卢亚男, 白瑞雪, 杨跃辉. 药物警戒在妊娠期药物治疗中的应用现状及建议[J]. 中国药物警戒, 2022, 19(3): 279-282.

LU Yanan, BAI Ruixue, YANG Yuehui. Current applications of pharmacovigilance in medications during pregnancy[J]. Chinese Journal of Pharmacovigilance, 2022, 19(3): 279-282.

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