中国药物警戒 ›› 2020, Vol. 17 ›› Issue (10): 724-725.
DOI: 10.19803/j.1672-8629.2020.10.16

• 安全与合理用药 • 上一篇    下一篇

氟比洛芬酯注射液致精神异常1例分析

易勤, 谭秋红, 罗圣平*   

  1. 株洲市中心医院,湖南 株洲412000
  • 收稿日期:2020-10-14 修回日期:2020-10-14 出版日期:2020-10-15 发布日期:2020-10-13
  • 通讯作者: *罗圣平,男,本科,主任药师,临床药学。E-mail:1483231497@qq.com
  • 作者简介:易勤,女,硕士,药师,临床药学。

Analysis of Mental Abnormality Induced by Flurbiprofen Axetil Injection

YI Qin, TAN Qiuhong, LUO Shengping*   

  1. Department of Pharmacy, Zhuzhou Central Hospital, Zhuzhou Hunan 412000, China
  • Received:2020-10-14 Revised:2020-10-14 Online:2020-10-15 Published:2020-10-13

摘要: 目的 提醒医务人员在使用氟比洛芬酯注射液时应密切关注用药安全。方法 分析1例车祸后右小腿疼痛伴活动受限的患者,因术后使用氟比洛芬酯注射液镇痛而导致的精神异常的病例资料。结果 该患者出现神志不清,胡言乱语,躁动等精神异常表现可能由氟比洛芬酯注射液引起的,及时停药后,患者家属诉未出现之前的症状,患者无神经系统后遗症。结论 氟比洛芬酯注射液导致的精神异常发生率低,及时停药预后良好,但容易掩盖病情,应引起临床重视。

关键词: 氟比洛芬酯注射液, 不良反应, 精神异常

Abstract: Objective To remind the medical staff to pay close attention to medication safety of flurbiprofen axetil injection. Methods A case of right leg pain with limited movement after traffic accident was retrospectively analyzed, which became mental abnormality caused by postoperative analgesia with flurbiprofen axetil injection. Results Flurbiprofen axetil injection may be the cause of mental abnormality such as delirium, gibberish, agitation, etc. After timely withdrawal of the drug, the family members of the patient complained that there were no previous symptoms, and the patient had no neurological sequelae. Conclusion Flurbiprofen axetil injection caused by low incidence of mental abnormality, timely withdrawal of the drug has a good prognosis, but it is easy to cover up the disease, which deserves attention.

Key words: flurbiprofen axetil injection, adverse reactions, mental abnormality

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