桂枝的薄层鉴别及含量测定

doi:10.19803/j.1672-8629.2022.04.08

中国药物警戒 ›› 2022, Vol. 19 ›› Issue (4): 380-383.
DOI: 10.19803/j.1672-8629.2022.04.08

桂枝的薄层鉴别及含量测定

欧阳罗丹, 肖苏萍^*, 周建新, 陈蒙, 邓哲, 周海燕, 杜杰, 王继永

中国中药有限公司,北京 100195

收稿日期:2021-03-03 出版日期:2022-04-15 发布日期:2022-04-15
通讯作者: ^*肖苏萍,女,硕士,正高级工程师,中药产品开发和质量控制。E-mail：xiaoladdy99@163.com
作者简介:欧阳罗丹,女,硕士,中药质量。
基金资助:
重大新药创制国家科技重大专项2018年度（2018ZX09721005-002）

TLC identification and content determination of Cinnamomi Ramulus

OUYANG Luodan, XIAO Suping^*, ZHOU Jianxin, CHEN Meng, DENG Zhe, ZHOU Haiyan, DU Jie, WANG Jiyong

China National of Traditional & Herbal Medicine Co.,Ltd., Beijing 100195, China

Received:2021-03-03 Online:2022-04-15 Published:2022-04-15

摘要/Abstract

摘要： 目的对《中华人民共和国药典》（2020年版）中桂枝的薄层鉴别和含量测定方法进行改进。方法以桂皮醛、肉桂酸、桂枝对照药材为对照品,对桂枝药材进行了薄层鉴别和含量测定条件的研究;并对不同产地的桂枝药材进行薄层鉴别和含量测定。结果薄层色谱斑点清晰,分离度好,易于检出,重现性佳。含量测定方法分离效率高,重复性好。结论所建立的桂枝薄层鉴别和含量测定方法简单、专属性强,可同时检测桂枝中的桂皮醛、肉桂酸,可为药典的修订提供参考。

关键词: 桂枝, 薄层鉴别, 含量测定, 桂皮醛, 肉桂酸

Abstract: Objective To improve the method for thin-layer identification and content determination of Cinnamomi Ramulus (Chinese Pharmacopoeia 2020 edition). Methods Cinnamaldehyde, Cinnamic acid and control medicinal materials of Cinnamomi Ramulus were used as reference materials to study the TLC identification of Cinnamomi Ramulus. The crude medicine of Cinnamomi Ramulus from different areas of production was identified by thin layer and content determination. Results TLC manifested clear spots, good separation, easy detection and good reproducibility. This content determination method had a high efficiency of separation and good repeatability. Conclusion The established method for thin-layer identification and content determination is simple and specific, which can simultaneously detect cinnamaldehyde and cinnamic acid in Cinnamomi Ramulus, and provide reference for the revision of the pharmacopoeia.

Key words: Cinnamomi Ramulus, thin layer identification, content determination, cinnamaldehyde, cinnamic acid

中图分类号:

R994.11R931

欧阳罗丹, 肖苏萍, 周建新, 陈蒙, 邓哲, 周海燕, 杜杰, 王继永. 桂枝的薄层鉴别及含量测定[J]. 中国药物警戒, 2022, 19(4): 380-383.

OUYANG Luodan, XIAO Suping, ZHOU Jianxin, CHEN Meng, DENG Zhe, ZHOU Haiyan, DU Jie, WANG Jiyong. TLC identification and content determination of Cinnamomi Ramulus[J]. Chinese Journal of Pharmacovigilance, 2022, 19(4): 380-383.

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桂枝的薄层鉴别及含量测定

TLC identification and content determination of Cinnamomi Ramulus

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