One case of gynecomastia induced by efavirenz tablets

doi:10.19803/j.1672-8629.20230041

Abstract

Abstract: Objective To explore one case of gynecomastia induced by efavirenz, and to provide reference for clinical prevention and treatment of the adverse reactions. Methods The process of treating one patient who had developed gynecomastia after taking efavirenz was analyzed in order to investigate the mechanism by which efavirenz caused gynecomastia and to rule out the possibility of other drugs. Results The patient developed unilateral gynecomastia after taking efaveranz. The breast discomfort was alleviated 2 months after withdrawal of efaveran and surgical treatment. Conclusion Gynecomastia caused by efavirenz may be related to the effect of estrogen/androgen. During medication, breasts should be examined regularly for the sake of early identification and treatment.

Key words: efavirenz, gynecomastia, HIV, AIDS, adverse drug reactions, antiretroviral therapy, non-nucleoside reverse transcriptase inhibitors

CLC Number:

R978
R994.11

TANG Jiong, LIU Ying. One case of gynecomastia induced by efavirenz tablets[J]. Chinese Journal of Pharmacovigilance, 2023, 20(11): 1306-1308.

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