Classification and influencing factors of toxicity of Chinese medicine based on ancient books of materia medica

doi:10.19803/j.1672-8629.2022.04.01

Abstract

Abstract: Objective To propose ways of improving the current methods of toxicity classification of traditional Chinese medicine (TCM) based on the review of ancient records of toxicity of Chinese herbal medicines. Methods The literature research method was used to search for literature related to the toxicity of TCM in ancient Chinese herbal books and to clarify concepts of TCM toxicity, the evolution of toxicity classification of TCM, and the main determinants of the toxicity of TCM. Results The classification of the toxicity of TCM has undergone three-level classification, four-level classification, and five-level classification. The difference in genes, preparations, medications, and physique of patents will affect the toxicity of TCM. Conclusion A multi-level and multi-factor toxicity evaluation system for TCM should be established, involving the source of the medicine, methods of preparation, the time and dosage of the medicine used, and the condition of the patient.

Key words: toxicity of Chinese materia medica, toxicity classification of Chinese materia medica, ancient books of materia medica

CLC Number:

R281R994.13

FU Lu, JIN Yan, PENG Huasheng, YUAN Yuan. Classification and influencing factors of toxicity of Chinese medicine based on ancient books of materia medica[J]. Chinese Journal of Pharmacovigilance, 2022, 19(4): 349-352.

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