Abstract: ObjectiveTo probe into how to improve prescription quality and play the role of pharmacists in clinical treatment by means of prescription intervention. MethodsThe retrospective study was used to analyze data from the whole outpatient prescriptions between 2012 and 2014. The examples of irrational prescriptions were classified and analyzed. The reasons of errors were given, and the countermeasures were suggested. ResultsThere were 455 irrational prescriptions intervened from 2012 to 2014. The rate of the irrational prescriptions was reduced from 2.4 to 0.6 (P=6.6×10^-32, P<0.05). Dermatology, cardiology internal, endocrinology, otolaryngology and gastroenterology were most frequently involved in irrational prescriptions. ConclusionInterventions are effective. There were still problems in prescription writing and rational drug use, which need further improvement in order to ensure the patient’s safety. Pharmacists must play the role of professionals.

Key words: intervention on prescriptions, outpatient pharmacy, countermeasure