Abstract: Objective To investigate the medication and compatibility of Sophorae tonkinensis Radix et Rhizoma in prescriptions of traditional Chinese medicine from a hospital, so as to provide guidance for medication safety and rationality in clinic. Methods Prescriptions with Sophorae tonkinensis Radix et Rhizoma in 2015 were selected from the hospital, and the medication dosage, department distribution, clinical application, single ingredient as well as the category were then statistically analyzed respectively. Results The prescriptions with Sophorae tonkinensis Radix et Rhizoma, of which the dosage was 6~9 g, were mainly used for 3 or 7 days, applied in otolaryngological department and pediatrics for the treatment of acute or chronic laryngopharyngitis, tonsillitis and cold. Besides, medicines used compatibly with Sophorae tonkinensis Radix et Rhizoma were those of heat-clearing medicine, dispelling phlegm drug, deficiency-supplementing medicine, drugs for relieving exterior syndrome, respectively by a ratio from high to low. What’s more, single ingredient used compatibly with Sophorae tonkinensis Radix et Rhizoma were Glycyrrhizae Radix et Rhizoma, Scutellariae Radix,Belamcandae Rhizoma, Platycodonis Radix, Scrophulariae Radix, respectively by a ratio from high to low. Conclusion Clinical medication of Sophorae tonkinensis Radix et Rhizoma prescriptions in this hospital is rather unreasonable. Thus, supervision and administration should be strengthened to raise the rationality and reduce the side effects.

Key words: Sophorae tonkinensis Radix et Rhizoma, prescription of traditional Chinese medicine, mdication analysis