TLC identification and content determination of Cinnamomi Ramulus

doi:10.19803/j.1672-8629.2022.04.08

Abstract

Abstract: Objective To improve the method for thin-layer identification and content determination of Cinnamomi Ramulus (Chinese Pharmacopoeia 2020 edition). Methods Cinnamaldehyde, Cinnamic acid and control medicinal materials of Cinnamomi Ramulus were used as reference materials to study the TLC identification of Cinnamomi Ramulus. The crude medicine of Cinnamomi Ramulus from different areas of production was identified by thin layer and content determination. Results TLC manifested clear spots, good separation, easy detection and good reproducibility. This content determination method had a high efficiency of separation and good repeatability. Conclusion The established method for thin-layer identification and content determination is simple and specific, which can simultaneously detect cinnamaldehyde and cinnamic acid in Cinnamomi Ramulus, and provide reference for the revision of the pharmacopoeia.

Key words: Cinnamomi Ramulus, thin layer identification, content determination, cinnamaldehyde, cinnamic acid

CLC Number:

R994.11R931

OUYANG Luodan, XIAO Suping, ZHOU Jianxin, CHEN Meng, DENG Zhe, ZHOU Haiyan, DU Jie, WANG Jiyong. TLC identification and content determination of Cinnamomi Ramulus[J]. Chinese Journal of Pharmacovigilance, 2022, 19(4): 380-383.

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