Yi medicine Micromeria biflora (Buch.Ham.ex D.Don)Benth. standard decoction

doi:10.19803/j.1672-8629.20210458

Abstract

Abstract: Objective To prepare Yi Medicine Micromeria biflora(Buch.Ham.ex D.Don)Benth. standard decoction and to study the quality standard. Methods Fifteen batches of Micromeria biflora(Buch.Ham.ex D.Don)Benth. standard decoction were prepared using the standard method. With rosmarinic acid as the quantitative detection index, the transfer rate and extraction rate were calculated and an HPLC characteristic chromatogram analysis method was established. Results According to the measurement of 15 batches of Micromeria biflora(Buch.Ham.ex D.Don)Benth. standard decoction, the transfer rate ranged from 34.11% to 104.72% and extraction rate from 11.9 % to 15.1 %. Similarity Evaluation System for Chromatographic Fingerprint of TCM (2012) was used to analyze and compare the characteristic chromatograms so that 23 common peaks were determined and 3 of them were identified. Moreover, the similarities were all over 0.90. Conclusion This determination method displays good precision, stability and repeatability, which can provide reference for quality control of Micromeria biflora(Buch.Ham.ex D.Don)Benth.

Key words: Yi medicine, Micromeria biflora(Buch.Ham.ex D.Don)Benth., rosmarinic acid, prepared drugs in pieces, standard decoction, characteristic chromatogram

CLC Number:

R917.101

WANG Meng, ZHI Yajing, QIE Lanxia, GUO Jiahui, CAI Yuluo, NIU Liying. Yi medicine Micromeria biflora (Buch.Ham.ex D.Don)Benth. standard decoction[J]. Chinese Journal of Pharmacovigilance, 2022, 19(12): 1315-1320.

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