Abstract: Objective To compare current prices of antineoplastic drugs and conduct an empirical analysis of irrationality.Methods Comparative analysis of prices was used to compare the prices of original drugs, generic drugs, antineoplastic drugs, first-line antineoplastic drugs and targeting agents. Results The price range between original and generic drugs was 32.28, which was significant difference. The average range, average value, and standard deviation of various antineoplastic drugs prices were 194.7, 36.44, and 58.01, respectively. The prices of first-line drugs recommended by the anti-tumor treatment guidelines varied widely. For example, the range of paclitaxel was 5.33, and the range of domestic drugs with the same specifications was between 33.3 and 144.89.Conclusion There is a large price range and a large variety of antineoplastic drugs with different specifications in China. A series of measures needs to be taken to improve the mechanism of pricing, strike a balance between prices of antineoplastic drugs, and solve the contradiction between the development of the pharmaceutical industry and drug accessibility.

Key words: price comparison analysis, antineoplastic drugs, drug prices, rationality