Chinese Journal of Pharmacovigilance ›› 2020, Vol. 17 ›› Issue (8): 539-542.
DOI: 10.19803/j.1672-8629.2020.08.19

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Literature Review of Research Progress in Drug Interactions between Ticagrelor and Morphine

LI Yu1, CHAI Shiwei1,*, WANG Xiaodan1, HAO limei2, LIU Fang1, XIN Xiaojing1   

  1. 1Department of Pharmacy, First Teaching Hospital of Tianjin University of TCM, Tianjin 300380, China;
    2Cardiovascular Department, First Teaching Hospital of Tianjin University of TCM, Tianjin 300380, China
  • Received:2020-07-31 Revised:2020-07-31 Online:2020-08-15 Published:2020-07-31

Abstract: Ticagrelor and morphine are often used in combination for the treatment of AMI. Studies have found that ticagrelor has a poor drug interaction with morphine, but there are relatively few studies on the interactions betweenof the two drugs. The aim of this review is intendedwas to summarize the pharmacokinetic-pharmacodynamic interactions between ticagrelor and morphine, and further explore theits mechanism and measures of improvement measures to provide guidance for clinical rational drug use.

Key words: ticagrelor, morphine, drug interaction

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