种子类有毒药材微性状及超微结构研究

doi:10.19803/j.1672-8629.2022.04.03

中国药物警戒 ›› 2022, Vol. 19 ›› Issue (4): 357-360.
DOI: 10.19803/j.1672-8629.2022.04.03

• 毒性中草药研究与利用专栏 • 上一篇下一篇

种子类有毒药材微性状及超微结构研究

王利丽, 刘孟奇, 王海春, 宋晓宇, 陈随清^*

河南中医药大学中药资源与化学重点实验室,河南郑州 450046

收稿日期:2021-10-30 发布日期:2022-04-15
通讯作者: ^*陈随清,男,博士,教授,中药质量标准。E-mail：suiqingchen@163.com
作者简介:王利丽,女,博士,副教授,中药质量评价。
基金资助:
国家科技基础资源调查专项（2018FY100802-03）

Micromorphology and ultrastructure of poisonous medicinal materials of seeds

WANG Lili, LIU Mengqi, WANG Haichun, SONG Xiaoyu, CHEN Suiqing^*

Henan Key Laboratory of Chinese Medicine Resources and Chemistry (Henan University of Chinese Medicine, Zhengzhou Henan 450046, China

Received:2021-10-30 Published:2022-04-15

摘要/Abstract

摘要： 目的利用体视显微镜、扫描电子显微镜对莨菪子等8种《中华人民共和国药典》（2020年版）及地方品种收载的有毒种子类药材进行微性状及超微结构研究,为有毒中药的鉴别提供依据。方法收集种子类药材,利用体视显微镜、扫描电子显微镜对其表面、横切面微形态进行观察,总结药材微性状及超微结构特征。结果从形状、大小、表面特征、断面特征等方面对微性状进行描述,对其性状鉴别特征进行有效补充和提高;从表面特征及附属物特征对粉碎后的药材超微结构进行总结,对粉碎后有毒药材的显微鉴别提供专属性较强的鉴别依据。结论因大小、形态及表面特征差异较大,微性研究能快速检出种子类药材;对于已经呈粉末性的药材,超微结构观察易识别出其特征,从而防止误用及混用。

关键词: 种子, 有毒药材, 微性状, 超微结构

Abstract: Objective To observe the micromorphology and ultrastructure of poisonous seed herbs using the stereomicroscope and scanning electron microscope (SEM). Methods After seed herbs were collected, the surface micromorphology of the herbs was observed under a stereomicroscope and SEM, and their surface and transverse characteristics were recorded. Results The micromorphology of these herbs was described in terms of the shape, size, surface and section characteristics. The identification of properties of these herbs was improved; The ultrastructure of crushed materials was summarized to facilitate the identification of crushed poisonous seed herbs. Conclusion Due to the large differences in size, shape and surface characteristics, microscopic studies can quickly detect seed medicinal materials; for medicinal materials that are already powdery, ultrastructural observation can easily identify their characteristics, thereby preventing misuse and mixed use.

Key words: seeds, poisonous medicinal materials, micromorphology, ultrastructure

中图分类号:

R282R994

王利丽, 刘孟奇, 王海春, 宋晓宇, 陈随清. 种子类有毒药材微性状及超微结构研究[J]. 中国药物警戒, 2022, 19(4): 357-360.

WANG Lili, LIU Mengqi, WANG Haichun, SONG Xiaoyu, CHEN Suiqing. Micromorphology and ultrastructure of poisonous medicinal materials of seeds[J]. Chinese Journal of Pharmacovigilance, 2022, 19(4): 357-360.

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种子类有毒药材微性状及超微结构研究

Micromorphology and ultrastructure of poisonous medicinal materials of seeds

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