中国药物警戒 ›› 2020, Vol. 17 ›› Issue (12): 946-948.
DOI: 10.19803/j.1672-8629.2020.12.22

• 安全与合理用药 • 上一篇    

克拉霉素片致迟发型过敏反应1例分析

刘静静, 王亦磊, 王彤, 康艳生, 张伟, 徐小亚, 常人元, 王晓琴*   

  1. 榆林市第一医院药剂科,陕西榆林 719000
  • 收稿日期:2020-02-21 修回日期:2020-12-07 出版日期:2020-12-15 发布日期:2020-12-07
  • 通讯作者: *王晓琴,女,在读硕士,主管药师,临床药学。E-mail:845034031@qq.com
  • 作者简介:刘静静,女,硕士,主管药师,临床药学。

Analysis of One Case of Delayed Anaphylaxis Induced by Clarithromycin Tablets

LIU Jingjing, WANG Yilei, WANG Tong, KANG Yansheng, ZHANG Wei, XU Xiaoya, CHANG Renyuan, WANG Xiaoqin*   

  1. Department of Pharmacy,The First Hospital of Yulin,Yulin Shaanxi 719000,China
  • Received:2020-02-21 Revised:2020-12-07 Online:2020-12-15 Published:2020-12-07

摘要: 目的 分析1例克拉霉素致迟发型过敏反应,为临床安全用药提供参考。方法 对患者服用的药物进行关联性评价,并对其进行文献分析。结果 患者敏感体质,迟发型过敏反应为克拉霉素所致。经过积极抗过敏治疗,患者痊愈。结论 克拉霉素为低敏性药物,亦可致迟发型过敏反应,但一般症状较轻微,敏感体质慎用。

关键词: 克拉霉素, 药品不良反应, 迟发型过敏反应

Abstract: Objective To analyze one case of delayed anaphylaxis induced by clarithromycin and provide safe references for clinical prescriptions.Methods To evaluate the relevance between drugs taken by patients and analyze the literature.Results The patient was sensitive constitution and delayed allergic reaction were caused by clarithromycin, after the antiallergic treatment, the patients recovered.Conclusion Clarithromycin has a low incidence of anaphylaxis and can caused delayed anaphylaxis with mild general symptoms. The patient of sensitive constitution should be used with caution.

Key words: clarithromycin, adverse drug reactions, delayed anaphylaxis

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