中国药物警戒 ›› 2010, Vol. 7 ›› Issue (7): 435-438.

• 药品不良反应监测 • 上一篇    下一篇

471例药物胃肠道不良反应回顾性分析

曹军, 陈苏宁, 文爱东*   

  1. 第四军医大学西京医院药剂科,陕西 西安 710032
  • 收稿日期:2016-02-22 修回日期:2016-02-22 出版日期:2010-07-08 发布日期:2016-02-22
  • 通讯作者: 文爱东,男,主任药师,临床药学,药剂学。E-mail:adwen@fmmu.edu.cn
  • 作者简介:曹军,男,本科,临床药学,药剂学。

Retrospective Case Analysis of 471 Patients with Adverse Drug Reaction of Gastrointestinal Tract

CAO Jun, CHEN Su-ning, WEN Ai-Dong*   

  1. Department of Pharmacy-Xingjing Hospital. Fourth Military Medical University, Shanxi Xi’an 710033,China
  • Received:2016-02-22 Revised:2016-02-22 Online:2010-07-08 Published:2016-02-22

摘要: 目的 对我院5年来药物引起的471例胃肠道不良反应进行回顾性分析,为临床合理用药和预防胃肠道不良反应提供参考。方法 对我院2005~2008年收集的471例胃肠道不良反应报表进行分类统计和分析。结果 药品引发的胃肠道不良反应涉及201个品种,抗感染药居首位(218例,占46.28%),其次是中药制剂(88例,占18.68%);55岁以上的患者居多(占36.94%);口服给药引发胃肠道不良反应为257例(占54.57%)。结论 临床应重视胃肠道不良反应的报告和致病原因,从而加强胃肠道不良反应的预防及监测,以减少和避免胃肠道不良反应的发生,保障患者用药合理、安全、有效。

关键词: 胃肠道系统, 药品不良反应

Abstract: Objective Over the past five years 471 patients drug-induced adverse drug reaction of gastrointestinal tract in our hospital were retrospectively analyzed to provide reference for the clinical reasonable medication and obviating adverse drug reaction of gastrointestinal tract. Methods 471 adverse drug reaction of gastrointestinal tract cases col-lected from 2005 to 2008 in our hospital were analyzed statistically. Results 471 adverse drug reaction of gastrointestinal tract cases refered to 201 kinds of drugs. Of which anti-infective agents occupied the first place which had 218 cases(46.28%).Followed by the traditional Chinese medicine which had 88 cases(18.68%).The majority of patients(36.94%) were over 55-years-old, and 257 cases(54.57%) were given orally. Conclusion Clinic should attach great importance to the reporting and principle and enhance to the obviating and detection of adverse drug reaction of gastrointestinal tract to reduce or avoid the occurrence of it, and to use reasonably safe and effective medications.

Key words: gastrointestinal tract system, adverse drug reaction(ADR)

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