中国药物警戒 ›› 2024, Vol. 21 ›› Issue (4): 451-453.
DOI: 10.19803/j.1672-8629.20230759

• 安全与合理用药 • 上一篇    下一篇

1例中西药联合治疗2型糖尿病患者痛风发作期的药学监护

陈丽叶1, 朱丽2,*, 贡磊磊3   

  1. 1昆山市中医医院药学部,江苏 昆山 215300;
    2中国中医科学院广安门医院药学部 北京 100053;
    3首都医科大学附属北京妇产医院药学部,北京 100026
  • 收稿日期:2023-12-05 出版日期:2024-04-15 发布日期:2024-04-18
  • 通讯作者: *朱丽,女,硕士,主管药师,临床药学。E-mail:zhuli881104@163.com
  • 作者简介:陈丽叶,女,硕士,主管中药师,临床中药学。
  • 基金资助:
    国家自然科学基金资助项目(82204698); 中国中医科学院广安门医院科研结余经费项目(2023085)

Pharmaceutical care of a patient with type 2 diabetes mellitus treated with a combination of traditional Chinese and Western medicine during acute exacerbation of gout

CHEN Liye1, ZHU Li2,*, GONG Leilei3   

  1. 1Department of Pharmacy, Kunshan Hospital of Traditional Chinese Medicine, Kunshan Jiangsu 215300, China;
    2Department of Pharmacy, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China;
    3Department of Pharmacy, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China
  • Received:2023-12-05 Online:2024-04-15 Published:2024-04-18

摘要: 目的 探讨临床药师在1例2型糖尿病患者痛风急性发作期治疗过程中的作用。方法 临床药师参与2型糖尿病患者痛风急性发作期的药物治疗,分析患者血糖控制不佳的药物原因,筛选降糖药物对血尿酸的影响,建议选用钠-葡萄糖共转运蛋白2抑制剂(SGLT-2i),同时优化降糖、痛风治疗的中西药方案。结果 患者肿痛症状明显缓解,血糖平稳下降。结论 临床药师通过参与1例2型糖尿病患者痛风急性发作期的药学监护,协助医师优化治疗方案,对患者进行个体化用药,在临床治疗过程中发挥了积极作用。

关键词: 2型糖尿病, 痛风, 急性发作, 中西药联合, 降糖, 高尿酸血症, 高脂血症, 血糖, 血尿酸

Abstract: Objective To explore the role of clinical pharmacists in the treatment of a patient with type 2 diabetes mellitus in the acute exacerbation stage of gout. Methods Clinical pharmacists participated in the treatment of a patient with type 2 diabetes mellitus in the stage of acute exacerbation, analyzed the drug-related causes of poor blood glucose control, studied the effect of hypoglycemic drugs on blood uric acid, recommended switch to SGLT-2i and optimized the Chinese and Western medicine regimens for hypoglycemic and gout treatment. Results The symptoms of swelling and pain were significantly alleviated, and the blood glucose decreased steadily. Conclusion Clinical pharmacists can play an active role in clinical treatment by participating in the pharmaceutical care of patients with type 2 diabetes mellitus during acute exacerbation of gout, assisting physicians in optimizing treatment plans, and providing individualized medication to patients.

Key words: diabetes mellitus type 2, gout, acute exacerbation, combination of traditional Chinese and Western medicine, reduction of blood glucose, hyperuricemia, hyperlipidemia, blood glucose, blood uric acid

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