青黛致绿色尿液1例分析

doi:10.19803/j.1672-8629.20210265

中国药物警戒 ›› 2023, Vol. 20 ›› Issue (2): 219-220.
DOI: 10.19803/j.1672-8629.20210265

青黛致绿色尿液1例分析

聂谦¹, 黄爱玲², 张宏才¹, 赵珏¹, 张德来¹, 谢文^1*

¹成都中医药大学附属医院心血管科,四川成都 610072;
²郫都区中医医院心血管科,四川成都 611730

收稿日期:2021-03-24 出版日期:2023-02-15 发布日期:2023-02-17
通讯作者: ^*谢文,男,本科,主任医师·硕导,中西结合临床研究。E-mail: Doctorxiewen2008@sohu.com
作者简介:聂谦,男,硕士,主治医师,中西结合临床研究。
基金资助:
国家重点研发计划（2017YFC1700401）; 四川省中医药管理局中医（民族医）专项（2100601-30299）; 成都中医药大学附属医院基金项目（20ZJ08）; 成都中医药大学医院专项基金(YYZX2020076)

Analysis of one case of green urine caused by Indigo Naturalis

NEI Qian¹, HUANG Ailing², ZHANG Hongcai¹, ZHAO Jue¹, ZHANG Delai¹, XIE Wen^1*

¹Department of Cardiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu Sichuan 610072, China;
²Department of Cardiology, Hospital of Traditional Chinese Medicine of Pidu District, Chengdu Sichuan 611730, China

Received:2021-03-24 Online:2023-02-15 Published:2023-02-17

摘要/Abstract

摘要： 目的对罕见绿色尿液的可能原因进行回顾,为临床诊疗提供思路。方法分析1例因发热、咳嗽不适,服用青黛后尿液变成绿色患者,分析其发生原因,并检索相关文献进行分析。结果患者尿常规以及其他相关实验室检查均未发现异常,尿液色谱分析发现了靛蓝。在告知患者停用中药并增加饮水后,尿液恢复正常的淡黄色。结论提示含有靛蓝成分的中药、中成药物可通过染色导致尿液变绿,但通常无害,需要与其他病理情况相鉴别。

关键词: 绿色尿液, 中药, 板蓝根, 大青叶, 青黛

Abstract: Objective To retrospectively study the possible causes of rare green urine in order to provide reference for clinical diagnosis and treatment. Methods The clinical data about one patient who had been hospitalized because of fever, cough and discomfort, and green urine after taking Indigo Naturalis, was reported and analyzed with a literature review. Results The patient’s urine routine examination and other related laboratory examinations showed no abnormalities, but chromatographic analysis of the urine revealed Indigo Naturalis. After the patient was told to stop using traditional Chinese medicine and drink plenty of water, the urine returned to normal light yellow. Conclusion Such elements of traditional Chinese medicines as Indigo Naturalis might cause urine to turn green by staining, but this change is usually harmless and needs to be distinguished from other pathological conditions.

Key words: green urine, traditional Chinese medicine, Banlangen, Daqingye, Indigo Naturalis

中图分类号:

R971
R994.1

聂谦, 黄爱玲, 张宏才, 赵珏, 张德来, 谢文. 青黛致绿色尿液1例分析[J]. 中国药物警戒, 2023, 20(2): 219-220.

NEI Qian, HUANG Ailing, ZHANG Hongcai, ZHAO Jue, ZHANG Delai, XIE Wen. Analysis of one case of green urine caused by Indigo Naturalis[J]. Chinese Journal of Pharmacovigilance, 2023, 20(2): 219-220.

参考文献

[1] LIN GW, WANG JY, GE JB. Practical Internal Medicine(实用内科学)[M]. 15th ed. Beijing: People’s Health Publishing House, 2017: 1918-2146.
[2] SZKODZIAK P, WONIAK A, SZKODZIAK F, et al.Green urine sign after laparoscopic chromopertubation as an effect of severe contrast intravasation: a report of three cases[J]. The Journal of International Medical Research, 2020, 48(8): 204-208.
[3] SEDHAI YR, BANIYA R, BASNYAT S.A case of propofol induced green urine[C]. American Thoracic Society 2020 International Conference, Philadelphia, 2020: 15-20.
[4] RAWAL G, SANKALP Y.Green urine due to propofol: a case report with review of literature[J]. Journal of Clinical and Diagnostic Research, 2015, 9(11): 3-4.
[5] LAM CW, WONG SYJ.A case of green urine due to a traditional Chinese medicine containing methylene blue[J]. New Zealand Medical Journal, 2010, 123: 71-76.
[6] SHIM YS, GIL HW, YANG JO, et al.A case of green urine after ingestion of herbicides[J]. Korean Journal of Internal Medicine, 2008, 23(1): 42-44.
[7] EHRIG F, WALLER S, MISRA M, et al.A case of‘green urine’[J]. Nephrology Dial Transplantation, 1999, 14(1): 190-192.
[8] GANGWANI MK, MUHAMMAD A, RANA A, et al.Green urine and altered mental status: a case of intoxication[J]. Journal of Ayub Medical College, Abbottabad, 2019, 19(2): 279-281.
[9] LEE D, CHUNG K, CHO JY, et al.Propofol-induced green urine in a patient with refractory status epilepticus[J]. Journal of Epilepsy Research, 2018(8): 97-99.
[10] KIM GE, KIM DY, YOO DK, et al.Green urine after general anesthesia with propofol: different responses in the same patient[J]. Anesthesia and Pain Medicine, 2017(12): 32-36.
[11] ELKOUNDI A, BENSGHIR M, BALKHI H, et al.Green urine in the operating room: the (Cloret Sign)[J] Qjm Monthly Journal of the Association of Physicians. 2018, 111(4): 265-266.
[12] SHIM YS, GIL HW, YANG JO, et al.A case of green urine after ingestion of herbicides[J]. Korean Journal International Medicine, 2008,23(1): 42-44.
[13] KAITLIN R, HOWARD AK, RANDY B.Fluorescent green urine in the emergency department[J]. Visual Journal of Emergency Medicine, 2018, 13: 137-138.
[14] AYCOCK RD, KASS DA.Abnormal urine color[J]. Southern Medical Journal, 2012, 105: 43-47.
[15] SUN D, HUANG SS.Green urine[J]. Canadian Medical Association , 2018, 190(8): E224.

青黛致绿色尿液1例分析

Analysis of one case of green urine caused by Indigo Naturalis

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	李嘉昕, 刘慧敏, 钱文秀, 马宁, 宋丽丽, 李遇伯. 基于中药系统毒理学数据库的中药致肾毒性及药物规律研究[J]. 中国药物警戒, 2024, 21(2): 173-180.
[2]	张建, 方慧华. 某院活血化瘀类中药注射剂使用评价标准建立的探索[J]. 中国药物警戒, 2024, 21(2): 185-189.
[3]	柏兆方, 湛小燕, 姚清, 陈思敏, 赵旭, 肖小河. 中药安全性评价理论创新与技术突破：病证毒理学[J]. 中国药物警戒, 2024, 21(1): 6-14.
[4]	郭龙鑫, 高云娟, 吴承钊, 龙敏娟, 祝胜凯, 宋海波, 赵旭, 肖小河. 基于不良反应监测大数据的中药药源性肝损伤风险信号新发现及易感因素初探[J]. 中国药物警戒, 2024, 21(1): 15-19.
[5]	方志娥, 李承贤, 柏兆方, 赵旭, 王伽伯, 肖小河. 马兜铃酸致肝癌的客观性研究与思考[J]. 中国药物警戒, 2024, 21(1): 20-24.
[6]	高源, 石伟, 肖小河, 柏兆方, 王伽伯. 特异质型药物性肝损伤体内评价模型研究进展[J]. 中国药物警戒, 2024, 21(1): 33-39.
[7]	李舒冉, 郭姗姗, 冀祖恩, 张薇, 崔晓兰. 新型冠状病毒感染后认知功能障碍的研究现状[J]. 中国药物警戒, 2024, 21(1): 59-64.
[8]	梅雨, 朱越, 张慧婷, 肖成荣, 高月, 马增春. 基于网络药理学和实验验证探讨中药复方CB001对低剂量辐射防护的作用机制[J]. 中国药物警戒, 2023, 20(8): 872-879.
[9]	丁子禾, 张彦琼, 林娜. 从脂质代谢途径探讨中药雷公藤“物-效/毒-靶”关联性的研究现状与展望[J]. 中国药物警戒, 2023, 20(5): 489-495.
[10]	聂黎行, 王馨平, 李静, 戴忠, 康帅, 马双成. 中药材（饮片）中马兜铃酸的含量分析及初步风险评估[J]. 中国药物警戒, 2023, 20(5): 553-559.
[11]	梁士兵, 余泽宇, 孔令垚, 晏利姣, 韩梅, 吴嘉瑞, 刘兆兰, 刘建平. 文献计量法在中药药物警戒领域中的应用价值及展望[J]. 中国药物警戒, 2023, 20(5): 591-594.
[12]	聂黎行, 陈佳, 张烨, 赵慧, 戴忠, 马双成. 板蓝根中外源性有害残留的全面检查及风险评估[J]. 中国药物警戒, 2023, 20(4): 379-382.
[13]	沈磐, 孙德志, 周维, 高月. 中药毒性预测研究进展与思考[J]. 中国药物警戒, 2023, 20(4): 473-479.
[14]	李舒冉, 郭姗姗, 崔晓兰. 单纯疱疹病毒I型与阿尔茨海默病相关性及中药抗单纯疱疹病毒I型感染研究进展[J]. 中国药物警戒, 2023, 20(3): 258-261.
[15]	王冠杰, 杜世芳, 刘宝生, 韩佳寅, 王振华, 路长飞. 107例药物性肝损伤不良反应报告分析[J]. 中国药物警戒, 2023, 20(3): 331-333.