中国药物警戒 ›› 2021, Vol. 18 ›› Issue (9): 855-859.
DOI: 10.19803/j.1672-8629.2021.09.12

• 安全与合理用药 • 上一篇    下一篇

国内外抗菌药物管理政策现状分析及其效果评价

朱雨蕾1, 李歆1,2,3,*   

  1. 1南京医科大学医政学院,江苏 南京 211166;
    2南京医科大学药学院,江苏 南京 211166;
    3南京医科大学全球健康中心,江苏 南京 211166
  • 收稿日期:2020-07-17 出版日期:2021-09-15 发布日期:2021-09-18
  • 通讯作者: *李歆,男,博士,教授·博导,药事管理与药物政策。Email：xinli@njmu.edu.cn
  • 作者简介:朱雨蕾,女,硕士,卫生政策和药物政策。
  • 基金资助:
    国家自然科学基金资助项目（71673147）

Current Policies and Evaluation of Antimicrobial Management

ZHU Yulei1, LI Xin1,2,3,*   

  1. 1School of Health Policy and Management, Nanjing Medical University, Nanjing Jiangsu 211166, China;
    2School of Pharmacy, Nanjing Medical University, Nanjing Jiangsu 210009, China;
    3Center for Global Health, Nanjing Medical University, Nanjing Jiangsu 211166, China
  • Received:2020-07-17 Online:2021-09-15 Published:2021-09-18

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摘要： 目的 梳理国内外抗菌药物管理政策效果评价领域的研究成果,为进一步完善抗菌药物管理政策提供参考,为后续相关研究提供方向和依据。方法 检索、筛选2011年1月1日至2019年12月31日国内外抗菌药物管理政策与干预的研究文献与政策文件。结果 纳入文献155篇,中文96篇,英文59篇。国内研究存在的问题：尚未形成成熟的评价体系;以单中心研究为主,样本代表性不足;缺乏对政策干预影响因素的深入研究。结论 建议进一步完善抗菌药物政策与干预评价体系;利用全国抗菌药物应用和细菌耐药监测网络,开展多中心协同研究;加强对政策干预影响因素研究,挖掘政策产生效果的积极因素和消极因素。

关键词: 抗菌药物管理, 政策, 干预, 效果, 评价

Abstract: Objective To summarize research findings related to effect evaluation of antimicrobial management policies at home and abroad in order to provide reference for the formulation of better policies on antimicrobial management and for related research. Methods Related databases were searched for literature and documents on the implementation of antimicrobial management policies that were published between January 2011 and February 2020. Results A total of 155 studies were finally collected, including 96 papers in Chinese and 59 ones in English. The evaluation system was far from full-fledged in China, research was mainly conducted in a single center, the sample representation was poor, and in-depth analysis of the influencing factors of policy interventions was scarce. Conclusion It is suggested that the evaluation system of antimicrobial policies and interventions should be further improved, and that multi-centered collaborative research be carried out at home based on nationwide antimicrobial use and bacterial resistance monitoring networks. Factors that can influence policy interventions need to be studied in order to find out what factors are positive or negative.

Key words: antimicrobial management, policy, intervention, effect, evaluation

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