Abstract: Objective To recognize drug fever and provide references for clinic. Methods A total of 78 cases of children undergoing drug fever was collected at our hospital, including the progress of diagnosis and treatment, medication and clinical manifestation. Results Antibaclerial accounted for 93.59% (73/75) of the total drugs which inducing drug fever. Pneumonia accounted for 65.38% (51/78) of the primary disease. Drug fever disappeared in 100% (78/78) cases in 1~2 days after suspedcted drugs were stopped. Conclusion Drug fever happens frequently in clinical treatments. The rules of drug fever needs to understand so as to reduce the harm.

Key words: drug fever, children, clinical observation