Abstract: This article introduces the executive summary of sentinel initiative, the sentinel system vision, progress building the sentinel system. Then it analyses the practical meaning and inspiration for ADR monitoring in China by the sentinel system and tries to establish the fundamental principle and developmental trend of ADR monitoring in the current period. This article suggests the project of drug safety data partner cooperation in China, which includes China adverse drug reaction sentinel union and data source cooperation.

Key words: sentinel system, active surveillance, project of drug safety data partner cooperation, China adverse drug reaction sentinel union, data source cooperation